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  • Deazaflavin


Deazaflavin is a derivative of flavin, a yellow-orange pigment found in plants, animals, and microorganisms. It is structurally similar to flavin, but with a nitrogen atom instead of an oxygen atom in the isoalloxazine ring. This small structural difference gives deazaflavin unique properties that make it useful in various applications.

At Wuxi Vega Science Co., Ltd., we take pride in our ability to produce high-quality deazaflavin that meets the needs of our customers. Our deazaflavin is approved for use as a food additive by regulatory bodies such as the European Food Safety Authority (EFSA) and the US Food and Drug Administration (FDA). It is also considered safe for use in pharmaceuticals and biotechnological applications.

Deazaflavin is found in various natural sources such as milk, cheese, eggs, and liver. In this article, we will explore the physical and chemical properties of Deazaflavin, its natural sources, and its potential health benefits.

Physical and Chemical Properties

Deazaflavin is a yellow or orange-colored compound with a molecular weight of 192.19 g/mol. It has a melting point of 267-269°C and is soluble in water and organic solvents such as ethanol and methanol. Deazaflavin is a stable compound that is not easily degraded by heat or light.

Natural Sources

Deazaflavin is present in various natural sources such as milk, cheese, eggs, and liver. It is also found in some plants and microorganisms. However, the concentration of Deazaflavin in these sources is relatively low compared to other flavin derivatives.

Revolutionizing Biocatalytic Production and Microbial Applications

In biocatalytic production, Deazaflavin shows exceptional potential, especially in renowned microorganisms like Escherichia coli and Saccharomyces cerevisiae. This highlights its role in the biocatalytic production of valuable compounds. The Deazaflavin cofactors, F420 and FO, further its application in biochemical oxidoreductases and photocatalytic systems.

Enhancing Biological and Photobiological Processes

Deazaflavin's role in enhancing the bioluminescence of Siberian earthworms Henlea sp. signifies its potential in biological light-emitting applications. As a potential NMN alternative in metabolic processes, Deazaflavin underscores its biochemical versatility.

Advancing Medical and Biotechnological Applications

Our deazaflavin derivatives, particularly TND1128, have shown promise as selective inhibitors of the human TDP2 enzyme, highlighting their potential in medical chemistry. Deazaflavin’s unique structure, compared to riboflavin, enables novel applications in xenobiotic metabolism and methanogenesis.

Broadening the Scope with Additional Insights

To offer a more complete understanding of Deazaflavin, we delve into its role in O2-stability, redox properties and functions, and its specific derivative, 8-Hydroxy-5-deazaflavin. The exploration of photoenzymatic reaction systems broadens its applicability in enzymatic processes.

Potential Health Benefits

Deazaflavin has been studied for its potential health benefits, including its ability to promote energy metabolism, boost the immune system, and protect against oxidative stress. It has also been found to have a role in maintaining normal nervous system function and cardiovascular health. In addition, Deazaflavin may have therapeutic potential in the treatment of anemia, nervous system disorders, and other conditions.


Supplement Application

Deazaflavin has several properties that make it useful in various applications, including:
Fluorescence: Deazaflavin exhibits strong fluorescence properties that make it useful in fluorescent labeling applications.
Stability: Deazaflavin is more stable than flavin, making it useful in applications where stability is critical, such as in the production of food additives and pharmaceuticals.
Redox properties: Deazaflavin can undergo redox reactions, making it useful in various enzymatic reactions, such as in the electron transport chain.



Deazaflavin is a bioactive substance that is a precursor of vitamin B2. It has various potential health benefits, including promoting energy metabolism, boosting the immune system, and protecting against oxidative stress. Deazaflavin is present in various natural sources such as milk, cheese, eggs, and liver. It is a stable compound with a relatively low concentration in natural sources. As with any dietary supplement, it is recommended to consult a healthcare professional before use.
Deazaflavin is a unique derivative of flavin with several properties that make it useful in various applications. Further research on the properties and applications of deazaflavin could lead to the development of new and innovative products and technologies. At Wuxi Vega Science Co., Ltd., we take pride in our ability to produce high-quality deazaflavin that meets the needs of our customers. If you are in need of deazaflavin for your pharmaceutical, food, or biotechnological applications, please contact us today. We are a professional manufacturer of deazaflavin and our product is of the highest quality, ensuring that you get the best results for your applications.

Further Information

Discover more about Deazaflavin and other innovative products like Nicotinamide Riboside Chloride, Vitamin C Tablets, or 3-Methyl-10-Ethyl-Deazaflavin at Wuxi Vega Science Co., Ltd.. Join us in pioneering new frontiers in science and technology. email to [email protected].

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